Clonal Complexes in Biomedical Ontologies

Biomedical ontologies.

Biomedical ontologies provide an organizational framework of the concepts involved in biological entities and processes in a system of hierarchical and associative relations that allows reasoning about biomedical knowledge. In contrast, biomedical terminologies promote a standard way of naming these concepts. Differences among various kinds of terminological systems can be briefly summarized as...

Semantic Similarity in Biomedical Ontologies

In recent years, ontologies have become a mainstream topic in biomedical research. When biological entities are described using a common schema, such as an ontology, they can be compared by means of their annotations. This type of comparison is called semantic similarity, since it assesses the degree of relatedness between two entities by the similarity in meaning of their annotations. The appl...

Chapter #2.5 BIOMEDICAL ONTOLOGIES

Ontology design is an important aspect of medical informatics, and reusability is a key issue that is determined by the level of compatibility among ontology concepts and among the theories of the biomedical domain they convey. In this article, we examine OpenGALEN, the UMLS Semantic Network, SNOMED CT, the Foundational Model of Anatomy, and the MENELAS ontology as well as descriptions of the b...

Session Introduction: Biomedical Ontologies

Developing Biomedical Ontologies Collaboratively

The development of ontologies that define entities and relationships among them has become essential for modern work in biomedicine. Ontologies are becoming so large in their coverage that no single centralized group of people can develop them effectively and ontology development becomes a community-based enterprise. In this paper we present Collaborative Protégé-a prototype tool that supports ...